5

THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE STATEMENTS OF OPERATIONS AND BALANCE SHEETS OF VICAL INCORPORATED AND IS QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.

1,000 9-MOS DEC-31-1997 JAN-01-1997 SEP-30-1997 6,704 35,588 1,350 0 0 43,642 6,681 4,251 47,392 1,879 1,259 0 0 155 44,099 47,392 0 5,473 0 8,911 0 0 150 (4,494) 0 (4,494) 0 0 0 (4,494) (.29) (.29)