POWER OF ATTORNEY



BE IT KNOWN TO ALL BY THESE PRESENT:



WHEREAS, Vical Incorporated (the "Company") has registered a class of its

equity securities under the Securities Exchange Act of 1934, as amended, and

may effect sales of its securities from time to time as permitted by the

Securities Act of 1933, as amended (collectively, the "Acts"); and



WHEREAS, the undersigned is and may be from time to time hereafter an officer

or director of the Company, and as such may be required or permitted by either

Act to execute or file reports, statements or other documents with the

Securities and Exchange Commission (the "Commission"), either on behalf of the

Company or on the undersigned's own behalf in either a personal or

representative capacity;



NOW, THEREFORE, the undersigned hereby constitutes and appoints Jill M. Church and Lynne M. Goldacker, or either of them, his attorney for his

and in his name, place and stead, to sign and file any and all documents as

the undersigned may be permitted or required to sign or file pursuant to the

Acts, whether on behalf of the Company or on the undersigned's own behalf in

either a personal or representative capacity, hereby giving and granting to

each of said attorneys full power and authority to do and perform all and

every act and thing whatsoever requisite and necessary to be done in and about

the premises, as fully to all intents and purposes as she might or could do if

personally present at the doing thereof, hereby ratifying, confirming and

approving all that each of said attorneys may or shall lawfully do, or cause

to be done, by virtue hereof.



IN WITNESS WHEREOF, the undersigned has hereunto set his name this 14th day of

September, 2006.



/s/ Alain P. Rolland

Signature